Natural and un-natural modifications

At Pepceuticals we are able to modify peptides to incorporate a range of moieties or stereocentres, some of which are listed in the table below.  Our staff is comprised of fully trained synthetic chemists, we are able to consider any chemically feasible adjustments to the peptide sequence.

N-Terminal Internal C-Terminal
Acetylation Biotin Amidation
Biotinylation Dabcyl Aldehydes
Cinnamoylation Dabsyl 7-Methoxycoumarin
Dabcyl Dansyl Lysine[Biotin]
Dansyl Fluoroscein Lysine[Flouroscein]
Dinitrophenyl Dehydro amino acids Pegylation
Flouroscein Hydroxproline Rhodamine TAMRA
Fmoc Citrulline Chloromethylketone
Formyl Homoarginine p-nitronilide
Myristoylation Lysine[Me] N-methylamide
N-methyl Ltsine[Me2] Monomethylarginine
Palmitoylation Lysine[Me3] Dimethylarginine (SDMA / ADMA)
Steroylation Arginine[Me] Peptide nucleic acid (PNA)
7-Methoxycoumarin Aminohexanoyl  
FITC Reduced bond

This list of modifications is not

exhaustive; please enquire if you

have a specific modification.

KLH 15N labelled
Pyroglutamoyl 13C labelled
BOC Aminohexanoic acid